Gene Medic was designed and programmed by Jason H. Moore, Ph.D. in 6502 assembly language for the Atari 2600. Dr. Moore is a Professor and Director of the Institute for Biomedical Informatics at the Perelman School of Medicine of the University of Pennsylvania with a research program focused on artificial intelligence and machine learning with application to understanding, preventing, and treating common human diseases. Motivation for this game from a lifelong interest in Atari video game systems and computers as well as a research interest in genomic medicine. Additional motivation came from the significant challenge of coding for the Atari 2600 that has no graphics chip, 128 bytes of RAM, and a code capacity of 4k or less on the ROM in the cartridge.
Here are some links to more information about Dr. Moore’s research interests.